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Prevalence of Narcotics-Induced Poisoning in Children under 18 Years of Age Referring to the Al-e-Jalil Educational and Therapeutic Center, Aq Qala, Golestan Province (2020-2022)
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Mohsen Yekrang1    , Mahsa Besharat * 2, Sima Besharat3 , Javad Enayat4 , Khadije Amjadi5 |
1- General Physician, Child and Adolescent Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
2- Assistant Professor of Pediatrics, Child and Adolescent Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran. , Mahsabe.mb@gmail.com
3- Associate Professor of Biomedical Sciences (Research-oriented), Clinical Research Development Unit, Shahid Sayad Shirazi Medical Training Center, Golestan University of Medical Sciences, Gorgan, Iran.
4- Assistant Professor of Allergy and Clinical Immunology, Child and Adolescent Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
5- Infectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, Iran. |
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Abstract: (895 Views) |
Background and Objective: Poisoning is one of the most common reasons for emergency department visits worldwide. Awareness of poisoning patterns helps identify risk factors and enables early diagnosis. In Iran, narcotics are among the main causes of poisoning in children. The current study aimed to determine the prevalence of narcotics-induced poisoning in children under 18 years old referring to the Al-e-Jalil Educational and Therapeutic Center in Aq Qala, Golestan Province.
Methods: This retrospective descriptive study was conducted on 36 children aged 1 month to 18 years (22 boys and 14 girls; mean age: 51.62±36.25 months) referring to the Al-e-Jalil Educational and Therapeutic Center in Aq Qala due to narcotics-induced poisoning from 2020 to 2022. Samples were included in the study using census. Patients’ medical records were reviewed and recorded in a checklist.
Results: The highest poisoning rate stemmed from the consumption of opium (69.4%), followed by methadone (25%). Decreased level of consciousness upon hospital admission was determined to be 66.7%. The interval between poisoning and hospital admission was 5.60±3.86 hours. The mean length of hospital stay was 1.25±0.80 days, and no patients died. Most children were male (61.1%), Turkmen (69.4%), and rural residents (86.1%). The highest cases of poisoning occurred in the summer (36.1%). The most common route of contact was oral (97.2%).
Conclusion: The poisoning rate with opium is higher compared to other narcotics. However, there is strong evidence of increased opium use among young people and some evidence of increased methadone use.
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Keywords: Poisoning [MeSH], Opium [MeSH], Pediatric Emergency Medicine [MeSH]
Article ID: Vol26-38 |
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Full-Text [PDF 768 kb]
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Type of Study: Original Articles |
Subject:
Pediatric
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1. Zhang Y, Yu B, Wang N, Li T. Acute poisoning in Shenyang, China: a retrospective and descriptive study from 2012 to 2016. BMJ Open. 2018 Aug;8(8):e021881. doi: 10.1136/bmjopen-2018-021881. [ DOI] [ PubMed] 2. Molla YM, Belachew KD, Ayehu GW, Teshome AA. Acute poisoning in children in Ethiopia: a cross-sectional study. Sci Rep. 2022 Nov;12(1):18750. doi: 10.1038/s41598-022-23193-x. [ DOI] [ PubMed] 3. Chien C, Marriott JL, Ashby K, Ozanne-Smith J. Unintentional ingestion of over the counter medications in children less than 5 years old. J Paediatr Child Health. 2003 May-Jun;39(4):264-69. doi: 10.1046/j.1440-1754.2003.00148.x. [ DOI] [ PubMed] 4. Torkashvand F, Sheikh Fathollahi M, Shamsi S, Kamali M, Rezaeian M. [Evaluating the Pattern of Acute Poisoning in Cases Referred to the Emergency Department of Ali-ebn Abi Taleb Hospital of Rafsanjan from October 2013 to September 2014]. JRUMS. 2015;14(4):311-24. [Article in Persian] [ Link] 5. Shadnia S, Esmaily H, Sasanian G, Pajoumand A, Hassanian-Moghaddam H, Abdollahi M. Pattern of acute poisoning in Tehran-Iran in 2003. Hum Exp Toxicol. 2007 Sep;26(9):753-56. doi: 10.1177/0960327107083017. [ DOI] [ PubMed] 6. Barary M, Pirzadeh M, Rezaeian N, Dadashnia M, Mohammadi-Daniali S, Pahlavani F, et al. An epidemiological study of poisoning cases in Babol (northern Iran) from 2015 to 2018. Caspian J Intern Med. 2021;12(1):35-44. doi: 10.22088/cjim.12.1.35. [ DOI] [ PubMed] 7. Alwan IA, Brhaish AS, Awadh AI, Misnan A, Rahim NAA, Tangiisuran B, et al. Poisoning among children in Malaysia: A 10-years retrospective study. PLoS One. 2022 Apr;17(4):e0266767. doi: 10.1371/journal.pone.0266767. [ DOI] [ PubMed] 8. Mottla ME, Bowler ME, Asgary R. Epidemiology, risk factors, and strategies to prevent and manage poisonings due to pharmaceuticals in children in low income and low-middle income countries: A systematic review. J Glob Health. 2023 Dec;13:04173. doi: 10.7189/jogh.13.04173. [ DOI] [ PubMed] 9. Zheng A, Bharmal A, Rajabali F, Turcotte K, Thomas L, Garis L, et al. Risk of non-medical drug overdose following prescription of opioids post-injury: A retrospective cohort study. Health Rep. 2022 Jul;33(7):3-12. doi: 10.25318/82-003-x202200700001-eng. [ DOI] [ PubMed] 10. Rodrigues Mendonça D, Menezes MS, Matos MA, Rebouças DS, Filho JN, de Assis RS, et al. Acute Poisoning in Children in Bahia, Brazil. Glob Pediatr Health. 2016 Feb;3:2333794X15623243. doi: 10.1177/2333794X15623243. [ DOI] [ PubMed] 11. Mowry JB, Spyker DA, Brooks DE, McMillan N, Schauben JL. 2014 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 32nd Annual Report. Clin Toxicol (Phila). 2015;53(10):962-1147. doi: 10.3109/15563650.2015.1102927. [ DOI] [ PubMed] 12. Haresabadi M, Sedaghat M, Vejdani M, Ahrari S, Toghian CHaharsougi N, Momeni A. [Epidemiologic Study of acute poisoning in children aged under 12 years referred to Imam Reza hospital, 2010-2012]. North Khorasan University of Medical Sciences. 2013;5(1):47-52. doi: 10.29252/jnkums.5.1.47. [ Link] [ DOI] 13. Chouhdari A, Farnaghi F, Hassanian-Moghaddam H, Zamani N, Sabeti S, Shahrabi Farahani H. Blood Lead Levels in Opium-Poisoned Children: One Cross-Sectional Study in Iran. Addict Health. 2020 Jul;12(3):159-66. doi: 10.22122/ahj.v12i3.268. [ DOI] [ PubMed] 14. Kashani P, Safari S, Hatamabadi H, Arhami Dolatabadi A, Manouchehrifar M, Dokht Tabrizi M. Characteristics of Methadone Intoxicated Children Presenting to Emergency Department; a Cross Sectional Study. Emerg (Tehran). 2017;5(1):e80. doi: 10.22037/emergency.v5i1.18780. [ DOI] [ PubMed] 15. Atighi Y, Eizadi-Mood N, Mansourian M, Zamani A, Saffaei A, Sabzghabaee AM. Predictive Factors of Treatment Outcomes for Hospital Care in Children with Acute Methadone Poisoning. J Res Pharm Pract. 2018 Oct-Dec;7(4):200-204. doi: 10.4103/jrpp.JRPP_16_141. [ DOI] [ PubMed] 16. Keka A, Ramosaj A, Toro H, Azemi M, Baloku A, Sylaj B, et al. Acute poisoning in children; changes over the years, data of pediatric clinic department of toxicology. Journal of Acute Disease. 2014;3(1):56-58. doi: 10.1016/S2221-6189(14)60012-3. [ Link] [ DOI] 17. Teklemariam E, Tesema S, Jemal A. Pattern of acute poisoning in Jimma University Specialized Hospital, South West Ethiopia. World J Emerg Med. 2016;7(4):290-93. doi: 10.5847/wjem.j.1920-8642.2016.04.009. [ DOI] [ PubMed] 18. Abula T, Wondmikun Y. The pattern of acute poisoning in a teaching hospital, north-west Ethiopia. Ethiop Med J. 2006 Apr;44(2):183-89. [ PubMed] 19. Sabzi Z, Soltani Pasha H, Azartash B, Sabzi P. [The study of Poisoning in Children Refred to TaleghaniMedical-Educational Centre of Gorgan, 2009]. J Res Dev Nurs Midw. 2010;7(2):76-82. [Article in Persian] [ Link] 20. Shadnia S, Rahimi M, Hassanian-Moghaddam H, Soltaninejad K, Noroozi A. Methadone toxicity: comparing tablet and syrup formulations during a decade in an academic poison center of Iran. Clin Toxicol (Phila). 2013 Sep-Oct;51(8):777-82. doi: 10.3109/15563650.2013.830732. [ DOI] [ PubMed] 21. Alghadeer S, Alrohaimi M, Althiban A, Kalagi NA, Balkhi B, Khan AA. The patterns of children poisoning cases in community teaching hospital in Riyadh, Saudi Arabia. Saudi Pharm J. 2018 Jan;26(1):93-97. doi: 10.1016/j.jsps.2017.10.007. [ DOI] [ PubMed] |
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Yekrang M, Besharat M, Besharat S, Enayat J, Amjadi K. Prevalence of Narcotics-Induced Poisoning in Children under 18 Years of Age Referring to the Al-e-Jalil Educational and Therapeutic Center, Aq Qala, Golestan Province (2020-2022). J Gorgan Univ Med Sci 2024; 26 (4) :64-69 URL: http://goums.ac.ir/journal/article-1-4425-en.html
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